Catalog Number: 2035
Alternate Names: Bis(31/31'){Cys31, Nva34]NPY(27-36)-NH2}
Biological Activity
Potent and highly selective NPY Y5 receptor agonist (Ki values are 0.85, 42, 3015 and 245 nM at Y5, Y1, Y2 and Y4 receptors respectively). Stimulates food intake gradually following intrahypothalamic administration in rats.
Technical Data
  • M.Wt:
    2597.09
  • Formula:
    C116H186N36O28S2
  • Sequence:
    YINLCTRXRY YINLCTRXRY*

    (Modifications: X = Nva, Tyr-10 = C-terminal amide, X* = Nva, Tyr-10* = C-terminal amide, Disulfide bridge between 5 - 5*)

  • Solubility:
    Soluble to 10 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    172997-92-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Bis(31/31'){Cys31, Nva34]NPY(27-36)-NH2}: a neuropeptide Y (NPY) Y5 receptor selective agonist with a latent stimulatory effect on food intake in rats.
    Balasubramaniam et al.
    Peptides, 2002;23:1485

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