BYK 49187

Catalog # Availability Size / Price Qty
3735/1
Poly(ADP-ribose) Polymerase Inhibitors Small Molecule
1 Image
Description: PARP-1 and PARP-2 inhibitor

Chemical Name: 4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one

Purity: ≥98%

Product Details
Reviews

Biological Activity

PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively). Displays potent inhibitory activity against human PARP-1 in cell-free and cellular assays in vitro; reduces myocardial infarct size in vivo.

Technical Data

M.Wt:
335.4
Formula:
C19H21N5O
Solubility:
Soluble to 10 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
163120-31-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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