BYK 49187

   
Product Datasheet
Catalog Number:3735
Chemical Name:4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one
Product Details
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Biological Activity
PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively). Displays potent inhibitory activity against human PARP-1 in cell-free and cellular assays in vitro; reduces myocardial infarct size in vivo.
Technical Data
  • M.Wt:
    335.4
  • Formula:
    C19H21N5O
  • Solubility:
    Soluble to 10 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    163120-31-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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