Catalog Number: 4455
Chemical Name: 1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-L-proline
Biological Activity
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM). Also displays reversible, competitive inhibition of leukotriene A4 (LTA4) hydrolase.
Technical Data
  • M.Wt:
    217.29
  • Formula:
    C9H15NO3S
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    62571-86-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effects of early captopril treatment and its removal on plasma angiotensin converting enzyme (ACE) activity and arginine vasopressin in hypertensive rats (SHR) and normotensive rats (WKY).
    Zhang et al.
    Clin.Exp.Hypertens., 1996;18:201
  2. Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril.
    Orning et al.
    J.Biol.Chem., 1991;266:16507
  3. LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein.
    Fujita and Yoshikawa
    Immunopharmacology., 1999;44:123

Have you used Captopril?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information