Carboxy-PTIO, potassium salt

Discontinued Product

0772 has been discontinued.
View all Additional Nitric Oxide Compounds products.
Carboxy-PTIO, potassium salt | CAS No. 148819-94-7 | Additional Nitric Oxide Compounds
1 Image
Description: Stable, water-soluble deactivator of NO

Chemical Name: 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, potassium salt

Product Details
Citations (11)
Reviews

Biological Activity

A stable, water-soluble free radical that reacts stoichiometrically with NO. Almost twice as strong an inhibitor as N(ω)-nitroarginine or N-methylarginine.

Technical Data

M.Wt:
315.38
Formula:
C14H16KN2O4
Solubility:
Soluble to 25 mM in ethanol and to 10 mM in water
Storage:
Desiccate at -20°C
CAS No:
148819-94-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Carboxy-PTIO, potassium salt

The citations listed below are publications that use Tocris products. Selected citations for Carboxy-PTIO, potassium salt include:

11 Citations: Showing 1 - 10

  1. Selective activation of microglia facilitates synaptic strength.
    Authors: Clark Et al.
    Cardiovasc Res  2015;35:4552
  2. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.
    Authors: Echeverría Et al.
    PLoS One  2014;9:e94146
  3. An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test.
    Authors: Carlile Et al.
    Life Sci  2012;90:267
  4. Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons.
    Authors: Jin Et al.
    Korean J Physiol Pharmacol  2012;16:211
  5. The role of vascular myoglobin in nitrite-mediated blood vessel relaxation.
    Authors: Ormerod Et al.
    Br J Pharmacol  2011;89:560
  6. The acute antinociceptive effect of HBO2 is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.
    Authors: Quock Et al.
    Brain Res  2011;1368:102
  7. Synaptic plasticity and NO-cGMP-PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning.
    Authors: Ota Et al.
    PLoS One  2010;5:e11236
  8. The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.
    Authors: Ping and Schafe
    Neural Plast  2010;2010:540940
  9. Synaptic plasticity and NO-cGMP-PKG signaling coordinately regulate ERK-driven gene expression in the lateral amygdala and in the auditory thalamus following Pavlovian fear conditioning.
    Authors: Ota Et al.
    Learn Mem  2010;17:221
  10. Modulation of inhibitory activity by nitric oxide in the thalamus.
    Authors: Yang
    J Neurophysiol  2007;97:3386

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Carboxy-PTIO, potassium salt

There are currently no reviews for this product. Be the first to review Carboxy-PTIO, potassium salt and earn rewards!

Have you used Carboxy-PTIO, potassium salt?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.