Carboxy-PTIO, potassium salt

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Carboxy-PTIO, potassium salt | CAS No. 148819-94-7 | Additional Nitric Oxide Compounds
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Description: Stable, water-soluble deactivator of NO

Chemical Name: 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, potassium salt

Product Details
Citations (11)

Biological Activity

A stable, water-soluble free radical that reacts stoichiometrically with NO. Almost twice as strong an inhibitor as N(ω)-nitroarginine or N-methylarginine.

Technical Data

Soluble to 25 mM in ethanol and to 10 mM in water
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Carboxy-PTIO, potassium salt

The citations listed below are publications that use Tocris products. Selected citations for Carboxy-PTIO, potassium salt include:

11 Citations: Showing 1 - 10

  1. Selective activation of microglia facilitates synaptic strength.
    Authors: Clark Et al.
    Cardiovasc Res  2015;35:4552
  2. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.
    Authors: Echeverría Et al.
    PLoS One  2014;9:e94146
  3. An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test.
    Authors: Carlile Et al.
    Life Sci  2012;90:267
  4. Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons.
    Authors: Jin Et al.
    Korean J Physiol Pharmacol  2012;16:211
  5. The role of vascular myoglobin in nitrite-mediated blood vessel relaxation.
    Authors: Ormerod Et al.
    Br J Pharmacol  2011;89:560
  6. The acute antinociceptive effect of HBO2 is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.
    Authors: Quock Et al.
    Brain Res  2011;1368:102
  7. Synaptic plasticity and NO-cGMP-PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning.
    Authors: Ota Et al.
    PLoS One  2010;5:e11236
  8. The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.
    Authors: Ping and Schafe
    Neural Plast  2010;2010:540940
  9. Synaptic plasticity and NO-cGMP-PKG signaling coordinately regulate ERK-driven gene expression in the lateral amygdala and in the auditory thalamus following Pavlovian fear conditioning.
    Authors: Ota Et al.
    Learn Mem  2010;17:221
  10. Modulation of inhibitory activity by nitric oxide in the thalamus.
    Authors: Yang
    J Neurophysiol  2007;97:3386


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