Potent inhibitor of α
- and β
-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.
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All Tocris products are intended for laboratory research use only.
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.
Gruters et al.
Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.
Welker et al.
Studies on the mechanism of castanospermine inhibition of α- and β-glucosidases.
Saul et al.