Home / Ubiquitin Conjugating Enzyme (E2) Inhibitors / CC 0651

CC 0651

4503 1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4503/10
CC 0651 | CAS No. 1319207-44-7 | Ubiquitin Conjugating Enzyme (E2) Inhibitors
1 Image
Description: Allosteric inhibitor of hCdc34

Chemical Name: (2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Allosteric inhibitor of human Cdc34. Inhibits hCdc34-mediated ubiquitination of p27Kip1 (IC50 = 1.72 μM). Exhibits selectivity for hCdc34 over Uba1, Ube2G1, UbcH7, UbcH5, Ube2N (Ubc13), Ube2R2, SMURF2, SspH1 and Rnf168.

Technical Data

M.Wt:
442.29
Formula:
C20H21Cl2NO6
Solubility:
Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1319207-44-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for CC 0651

The citations listed below are publications that use Tocris products. Selected citations for CC 0651 include:

1 Citation: Showing 1 - 1

  1. σ1 receptor ligands control a switch between passive and active threat responses.
    Authors: Rennekamp Et al.
    Nat Chem Biol  2016;12:552

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CC 0651

There are currently no reviews for this product. Be the first to review CC 0651 and earn rewards!

Have you used CC 0651?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.