CC 0651

Catalog # Availability Size / Price Qty
4503/10
Cat.No. 4503 - CC 0651 | C20H21Cl2NO6 | CAS No. 1319207-44-7
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Description: Allosteric inhibitor of hCdc34

Chemical Name: (2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Allosteric inhibitor of human Cdc34. Inhibits hCdc34-mediated ubiquitination of p27Kip1 (IC50 = 1.72 μM). Exhibits selectivity for hCdc34 over Uba1, Ube2G1, UbcH7, UbcH5, Ube2N (Ubc13), Ube2R2, SMURF2, SspH1 and Rnf168.

Technical Data

M.Wt:
442.29
Formula:
C20H21Cl2NO6
Solubility:
Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1319207-44-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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