Catalog Number: 4028
Chemical Name: (2E)-2-(1,3-Benzothiazol-2-yl)-3-[9-methyl-2-(3-methylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]acrylonitrile
Biological Activity
Reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Selective amongst RGS proteins, with greatest potency at RGS4. Inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo. Retains activity under reducing conditions.
Technical Data
  • M.Wt:
    450.51
  • Formula:
    C26H18N4O2S
  • Solubility:
    Soluble to 5 mM in DMSO with gentle warming
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    620112-78-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.
    Blazer et al.
    Mol.Pharmacol., 2010;78:524
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CCG 63802 include:

1 Citations: Showing 1 - 1

  1. A new model of nerve injury in the rat reveals a role of Regulator of G protein Signaling 4 in tactile hypersensitivity.
    Authors: Taccola Et al.
    Experimental Neurology 2016;286:1

Have you used CCG 63802?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information