CD3 epsilon Antibody

A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3 epsilon (Uniprot: P07766)

Predicted to react with Ape, Orangutan, Gibbon, Chimpanzee, Monkey, Elephant, Equine, Bovine, Sheep, Porcine, Canine, Feline, Rabbit, Rat, Mouse, Guinea Pig, Hamster, Opossum, Frog, Chicken.

Cell surface and cytoplasmic

T-Cell Marker

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Polyclonal

Rabbit

IgG

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

200ug/ml of antibody purified from rabbit anti-serum by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0 mg/ml. (NBP2-33116)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein A purified

10 mM PBS with 0.05% BSA

0.05% Sodium Azide

0.2 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.