Key Product Details

Species Reactivity

Human, Mouse, Bovine, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

A synthetic peptide made to a C-terminal region of human CDR2 [Swiss-Prot# Q01850]

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: rat (85%).

Localization

Cytoplasmic and Nuclear

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDR2 Antibody [DyLight 488]

Flow Cytometry: CDR2 Antibody [DyLight 488] [NB110-58345G] - Thymus epithelial cells CDR2. Image from verified customer review.

Applications for CDR2 Antibody [DyLight 488]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NB110-58345G in the following applications:

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CDR2

Recent News: CDR2s Link to PCD (please find the link below). www.hhmi.org/news/darnell20071105.html Using anti-Yo antibodies, three genes have been cloned (CDR 1-3). CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR2 is regulated by a post-transcriptional mechanism.

Alternate Names

CDR62, cerebellar degeneration-related protein (62kD), cerebellar degeneration-related protein 2, cerebellar degeneration-related protein 2, 62kDa, Major Yo paraneoplastic antigen, Paraneoplastic cerebellar degeneration-associated antigen, PCD17, Yo, Yo paraneoplastic antigen

Gene Symbol

CDR2

Additional CDR2 Products

Product Documents for CDR2 Antibody [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CDR2 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for CDR2 Antibody [DyLight 488] (1)

5 out of 5
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Customer Images


Showing  1 - 1 of 1 review Showing All
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  • Name: Erin Xu
    Application: Flow Cytometry
    Sample Tested: human thymic epithelial cells
    Species: Human
    Verified Customer | Posted 04/25/2014
    thymus epithelial cells CDR2
    CDR2 Antibody [DyLight 488] NB110-58345G

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Protocols

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FAQs for CDR2 Antibody [DyLight 488]

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  • Q: I'm looking for an antibody against human CDR2 to recognize thymic epithelial cells. You have several anti CDR2 antibodies. Are they against a thymic epithelial antigen or against the cerebellar degeneration-related protein 2, 62kDa?

    A: Yes, the specific antibody you have inquired about is against cerebellar degeneration-related protein 2, 62 kDa. Moreover, all of our CDR2 primaries are against the same target.

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