CGP 54626 hydrochloride

Key Product Details

Product Description

CGP 54626 hydrochloride is a potent, selective GABA_B receptor antagonist (IC₅₀ = 4 nM).

Licensing Information

Sold with the permission of Novartis Pharma AG

Product Specifications for CGP 54626 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CGP 54626 hydrochloride

The following data is based on the product molecular weight 444.76.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.50 mL	22.48 mL	44.97 mL
2.5 mM	0.90 mL	4.50 mL	8.99 mL
5 mM	0.45 mL	2.25 mL	4.50 mL
25 mM	0.09 mL	0.45 mL	0.90 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 52 publications citing the usage of this product.

• Kaupmann GABA_B-receptor subtypes assemble into functional heteromeric complexes. Nature 1998 PMID: 9872317
• Froestl Potent, orally active GABA_B receptor antagonists. Pharmacol.Rev.Comm.
• Brugger The action of new potent GABA_B receptor antagonists in the hemisected spinal cord preparation of the rat. Eur.J.Pharmacol. 1993 PMID: 8390938

Product Documents for CGP 54626 hydrochloride