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Chaetoglobosin A

Catalog #: 5804 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5804/1
Chaetoglobosin A | CAS No. 50335-03-0 | Antibiotics
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Description: Antibiotic; selectively induces apoptosis of CLL cells

Chemical Name: (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-3H-cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione

Purity: ≥98%

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Biological Activity

Chaetoglobosin A is an antibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G2 phase.

Technical Data

M.Wt:
528.64
Formula:
C32H36N2O5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
50335-03-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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