CHMP2B Antibody

Name: CHMP2B Antibody
Brand: Novus Biologicals
SKU: NBP2-15886
Price: 489 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-15886

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (99%), Chicken (94%), Mouse (99%), Porcine (99%), Rhesus Macaque (98%), Xenopus (91%). Backed by our 100% Guarantee.

Applications

Knockout Validated, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

View all CHMP2B Primary Antibodies »

Product Specifications

Immunogen

Full length human CHMP2B Recombinant protein.

Localization

Cytoplasm; cytosol; Late endosome membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Knockout (KO) Validated Rabbit CHMP2B Antibody (NBP2-15886) is a polyclonal antibody validated for use in WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CHMP2B Antibody

Western Blot: CHMP2B Antibody [NBP2-15886]

Western Blot: CHMP2B Antibody [NBP2-15886] - Sample (30 ug of whole cell lysate) A: HepG2 12% SDS PAGE gel, diluted at 1:2000.

Immunocytochemistry/ Immunofluorescence: CHMP2B Antibody [NBP2-15886]

Immunocytochemistry/Immunofluorescence: CHMP2B Antibody [NBP2-15886] - Confocal immunofluorescence analysis of methanol-fixed HeLa, using CHMP2B antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000.

Western Blot: CHMP2B Antibody [NBP2-15886] -

Western Blot: CHMP2B Antibody [NBP2-15886] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with CHMP2B antibody (NBP2-15886) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for CHMP2B Antibody

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CHMP2B

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq]

Long Name

Charged Multivesicular Body Protein 2B

Alternate Names

CHMP2.5, DMT1, Vps2-2, VPS2B

Gene Symbol

CHMP2B

UniProt

Q9UQN3 (Human)

Additional CHMP2B Products

Product Documents for CHMP2B Antibody

Download Product Datasheets

Download SDS

Product Specific Notices for CHMP2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.

Related Research Areas

Autophagy

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