Chorionic Gonadotropin beta Chain (hCG beta) Antibody (27E8) [Biotin]

Novus Biologicals | Catalog # NB110-8025B

Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

Sandwich ELISA

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 27E8
View all Chorionic Gonadotropin beta Chain (HCG beta) Primary Antibodies »

Product Specifications

Immunogen

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with native human HCG (whole molecule).

Reactivity Notes

Human.

Localization

Secreted

Specificity

This specifically recognizes beta subunit of hCG. It does not cross-react with hLH, hTSH, hFSH.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Chorionic Gonadotropin beta Chain (hCG beta) Antibody (27E8) [Biotin]

Application
Recommended Usage

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Chorionic Gonadotropin beta Chain (HCG beta)

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Long Name

Chorionic Gonadotropin beta Chain

Alternate Names

CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta

Gene Symbol

CGB3

Additional Chorionic Gonadotropin beta Chain (HCG beta) Products

Product Documents for Chorionic Gonadotropin beta Chain (hCG beta) Antibody (27E8) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Chorionic Gonadotropin beta Chain (hCG beta) Antibody (27E8) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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