Cisapride

  ( 4 citations )    
Product Datasheet
Catalog Number:1695
Alternate Names:R 51619
Chemical Name:(±)-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide
Product Details
Citations (4)
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Biological Activity
5-HT4 receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT4 receptor-dependent and -independent mechanisms, leading to increased intestinal motility.
Technical Data
  • M.Wt:
    465.95
  • Formula:
    C23H29ClFN3O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    81098-60-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cisapride include:

4 Citations: Showing 1 - 4
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  1. A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4).
    Authors: Padayatti Et al.
    Mol Cell Proteomics  2013;12:1259
  2. The Pharmacology of TD-8954, a Potent and Selective 5-HT(4) Receptor Agonist with Gastrointestinal Prokinetic Properties.
    Authors: Beattie Et al.
    Front Pharmacol  2011;2:25
  3. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  4. Modulation of spontaneous firing in rat subthalamic neurons by 5-HT receptor subtypes.
    Authors: Xiang Et al.
    J Neurophysiol  2005;93:1145

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