receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT4
receptor-dependent and -independent mechanisms, leading to increased intestinal motility.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Cisapride and a structural analogue, R 76,186, are 5-hydroxytryptamine4 (5-HT4) receptor agonists on the guinea-pig colon ascendens.
Briejer et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1993;347:464
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
Schuurkes et al.
Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors.
Taniyama et al.
The citations listed below are publications that use Tocris products. Selected citations for Cisapride include:
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