Cisapride

Key Product Details

Product Description

Cisapride is a 5-HT₄ receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT₄ receptor-dependent and -independent mechanisms, leading to increased intestinal motility.

Product Specifications for Cisapride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Cisapride

The following data is based on the product molecular weight 465.95.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.15 mL	10.73 mL	21.46 mL
5 mM	0.43 mL	2.15 mL	4.29 mL
10 mM	0.21 mL	1.07 mL	2.15 mL
50 mM	0.04 mL	0.21 mL	0.43 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 27 publications citing the usage of this product.

• Schuurkes Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig. J.Pharmacol.Exp.Ther. 1985 PMID: 3897516
• Taniyama Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors. J.Pharmacol.Exp.Ther. 1991 PMID: 1890614
• Briejer Cisapride and a structural analogue, R 76,186, are 5-hydroxytryptamine₄ (5-HT₄) receptor agonists on the guinea-pig colon ascendens. Naunyn Schmiedebergs Arch.Pharmacol. 1993 PMID: 8321323

Product Documents for Cisapride