Clonidine hydrochloride

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0690/100
Clonidine hydrochloride | CAS No. 4205-91-8 | Adrenergic alpha-2 Receptor Agonists
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Description: α2 agonist. Also I1 ligand

Chemical Name: 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride

Purity: ≥99%

Product Details
Citations (9)
Supplemental Products
Reviews (1)

Biological Activity

Clonidine hydrochloride is a prototypical I1 imidazoline receptor ligand. α2-adrenergic receptor agonist. Antihypertensive. Also thought to enhance autophagy; shown to increase LC3-II levels in PC12 cells.

Technical Data

M.Wt:
266.56
Formula:
C9H9Cl2N3.HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
4205-91-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Clonidine hydrochloride

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Behavioral pharmacology studies in rodents
By Anonymous on 01/04/2018
Application: Species: Rat

Behavioral pharmacology. Systemic blockade of alpha2- noradrenergic receptors. Dissolved in water at doses of 0.01-1.0 mg/mL and injected systemically in rats. Has sedative effects on motor movement.


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