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CometAssay Lysis Solution

Catalog #: 4250-050-01
37 Citations 1 Review Datasheet / COA / SDS
100 mL and 1000 mL (2 x 500 mL) available
Catalog # Availability Size / Price Qty
4250-010-01
4250-050-01
Product Details
Citations (37)
FAQs
Reviews (1)
Summary Product Datasheets

CometAssay Lysis Solution Summary

CometAssay Lysis Solution contains high salt and detergent and is suitable for use with either the alkaline or neutral comet assay protocol. 

Available as 100 mL or 1000 mL (2 x 500 mL) volumes.
 

Key Benefits

• Designed for use with CometAssay, FLARE, and CometChip.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended on the label.
Storage
Store the unopened product at room temperature. Do not use past expiration date.
Species
N/A

Limitations

For research use only. Not for diagnostic use.

Product Datasheets

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Product Datasheet
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Citations for CometAssay Lysis Solution

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

37 Citations: Showing 1 - 10
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  1. The WWP1-JARID1B axis sustains acute myeloid leukemia chemoresistance
    Authors: Fierro, C;Giovannini, S;Moriconi, V;Fiorilli, C;Panatta, E;Frezza, V;Corigliano, F;Pecorari, R;Li, Y;Zhou, J;Delvecchio, VS;Smirnov, A;Manteiga, JMG;Brendolan, A;Zhang, J;Shi, Y;Amelio, I;Candi, E;Melino, G;Bernassola, F;
    Proceedings of the National Academy of Sciences of the United States of America  2025-07-15
  2. Depletion of BRD9-mediated R-loop accumulation inhibits leukemia cell growth via transcription-replication conflict
    Authors: Lee, SY;Lee, SH;Kwak, MJ;Kim, JY;Perren, JO;Miller, KM;Kim, JJ;
    Nucleic acids research  2025-06-20
  3. Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation
    Authors: Sun, F;Ali, NN;Londoño-Vásquez, D;Simintiras, CA;Qiao, H;Ortega, MS;Agca, Y;Takahashi, M;Rivera, RM;Kelleher, AM;Sutovsky, P;Patterson, AL;Balboula, AZ;
    Nature communications  2024-11-01
  4. Assessment of the carcinogenic potential of particulate matter generated from 3D printing devices in Balb/c 3T3-1-1 cells
    Authors: Lim, C;Seo, D;
    Scientific reports  2024-10-14
  5. Temporal coordination of the transcription factor response to H2O2 stress
    Authors: Jose, E;March-Steinman, W;Wilson, BA;Shanks, L;Parkinson, C;Alvarado-Cruz, I;Sweasy, JB;Paek, AL;
    Nature communications  2024-04-23
  6. Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes
    Authors: Son, K;Takhaveev, V;Mor, V;Yu, H;Dillier, E;Zilio, N;Püllen, NJL;Ivanov, D;Ulrich, HD;Sturla, SJ;Schärer, OD;
    Nature communications  2024-02-15
  7. Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cells
    Authors: Meaza, I;Williams, AR;Lu, H;Kouokam, JC;Toyoda, JH;Croom-Perez, TJ;Wise, SS;Aboueissa, AE;Wise, JP;
    Toxicology and applied pharmacology  2023-10-05
  8. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding
    Authors: Shimizu, N;Hamada, Y;Morozumi, R;Yamamoto, J;Iwai, S;Sugiyama, KI;Ide, H;Tsuda, M;
    The Journal of biological chemistry  2023-06-29
  9. Frailty, Sex, and Poverty are Associated with DNA Damage and Repair in Frail, Middle-aged Urban Adults
    Authors: Smith, J;Hooten, N;Mode, N;Zonderman, A;Ezike, N;Kaushal, S;Evans, M;
    DNA Repair  2023-06-29
  10. Cellular photo(geno)toxicity of gefitinib after biotransformation
    Authors: El Ouardi, M;Tamarit, L;Vayá, I;Miranda, MA;Andreu, I;
    Frontiers in pharmacology  2023-06-07
  11. PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity
    Authors: Kim, S;Kim, Y;Kim, Y;Yoon, S;Lee, KY;Lee, Y;Kang, S;Myung, K;Oh, CK;
    PloS one  2023-05-19
  12. NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
    Authors: A Meroni, J Grosser, S Agashe, N Ramakrishn, J Jackson, P Verma, L Baranello, A Vindigni
    Science Advances, 2022-12-09;8(49):eabq0648.  2022-12-09
  13. Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma
    Authors: CY Hsieh, WC Chang, CC Lin, JH Chen, CY Lin, CH Liu, C Lin, MC Hung
    American journal of cancer research, 2022-11-15;12(11):5049-5061.  2022-11-15
  14. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
    Authors: M Yoshinaga, K Han, DW Morgens, T Horii, R Kobayashi, T Tsuruyama, F Hia, S Yasukura, A Kajiya, T Cai, PHC Cruz, A Vandenbon, Y Suzuki, Y Kawahara, I Hatada, MC Bassik, O Takeuchi
    Nature Communications, 2022-10-28;13(1):6435.  2022-10-28
  15. Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
    Authors: J Li, CA Koczor, KM Saville, F Hayat, A Beiser, S McClellan, ME Migaud, RW Sobol
    Cancers, 2022-07-22;14(15):.  2022-07-22
  16. Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients
    Authors: DT Stefanou, M Kouvela, D Stellas, K Voutetakis, O Papadodima, K Syrigos, VL Souliotis
    Biomedicines, 2022-05-26;10(6):.  2022-05-26
  17. Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor
    Authors: B Jiang, C Murray, BL Cole, JNM Glover, GK Chan, J Deschenes, RS Mani, S Subedi, JD Nerva, AC Wang, CM Lockwood, HC Mefford, SES Leary, JG Ojemann, M Weinfeld, CI Ene
    Scientific Reports, 2022-03-30;12(1):5386.  2022-03-30
  18. Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
    Authors: FB Rashed, D Diaz-Dussa, F Mashayekhi, D Macdonald, PN Nation, XH Yang, S Sokhi, AC Stoica, H El-Saidi, C Ricardo, R Narain, IH Ismail, LI Wiebe, P Kumar, M Weinfeld
    Redox Biology, 2022-03-21;52(0):102300.  2022-03-21
  19. Evaluation of phototoxicity induced by the anticancer drug rucaparib
    Authors: A Mateos-Puj, MC Jiménez, I Andreu
    Scientific Reports, 2022-03-02;12(1):3434.  2022-03-02
  20. Genetic vulnerabilities upon inhibition of DNA damage response
    Authors: C Wang, M Tang, Z Chen, L Nie, S Li, Y Xiong, KA Szymonowic, JM Park, H Zhang, X Feng, M Huang, D Su, T Hart, J Chen
    Nucleic Acids Research, 2021-08-20;0(0):.  2021-08-20
  21. Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage
    Authors: X Wu, B Wang
    Nature Communications, 2021-07-16;12(1):4373.  2021-07-16
  22. DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation
    Authors: W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ZM Zhang, JP Coan, J Yin, DI Kim, L Gao, L Cai, N Khudaverdy, B Çetin, DJ Patel, Y Wang, Q Cui, BD Strahl, O Gozani, KM Miller, SE O'Leary, PA Wade, GG Wang, J Song
    Nature Communications, 2021-05-03;12(1):2490.  2021-05-03
  23. Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors
    Authors: E Grimley, AJ Cole, TT Luong, SC McGonigal, S Sinno, D Yang, KA Bernstein, RJ Buckanovic
    Theranostics, 2021-01-20;11(8):3540-3551.  2021-01-20
  24. Super-resolution visualization of distinct stalled and broken replication fork structures
    Authors: DR Whelan, WTC Lee, F Marks, YT Kong, Y Yin, E Rothenberg
    PloS Genetics, 2020-12-28;16(12):e1009256.  2020-12-28
  25. Fanconi Anemia Pathway Activation by FOXM1 Is Critical to Bladder Cancer Recurrence and Anticancer Drug Resistance
    Authors: YG Roh, JY Mun, SK Kim, W Park, MS Jeong, TN Kim, WT Kim, YH Choi, IS Chu, SH Leem
    Cancers (Basel), 2020-05-30;12(6):.  2020-05-30
  26. Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS
    Authors: JAG Agúndez, E García-Mar, G García-Lai, MA Miranda, I Andreu
    Sci Rep, 2020-04-23;10(1):6879.  2020-04-23
  27. A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells
    Authors: M Wakita, A Takahashi, O Sano, TM Loo, Y Imai, M Narukawa, H Iwata, T Matsudaira, S Kawamoto, N Ohtani, T Yoshimori, E Hara
    Nat Commun, 2020-04-22;11(1):1935.  2020-04-22
  28. Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
    Authors: FA Alhumaydhi, D de O Lopes, DL Bordin, ASM Aljohani, CB Lloyd, MD McNicholas, L Milano, CF Charlier, I Villela, JAP Henriques, KE Plant, RM Elliott, LB Meira
    Sci Rep, 2020-02-10;10(1):2209.  2020-02-10
  29. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
    Authors: X Meng, Y Zhao, B Han, C Zha, Y Zhang, Z Li, P Wu, T Qi, C Jiang, Y Liu, J Cai
    Nat Commun, 2020-01-30;11(1):594.  2020-01-30
  30. Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro
    Authors: KJ Nytko, P Thumser-He, MS Weyland, S Scheidegge, CR Bley
    PLoS ONE, 2019-05-15;14(5):e0216744.  2019-05-15
  31. CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs
    Authors: M Mohiuddin, MM Rahman, JE Sale, CE Pearson
    Nucleic Acids Res., 2019-04-08;0(0):.  2019-04-08
  32. Marginal Zinc Deficiency and Environmentally Relevant Concentrations of Arsenic Elicit Combined Effects on the Gut Microbiome
    Authors: CA Gaulke, J Rolshoven, CP Wong, LG Hudson, E Ho, TJ Sharpton
    mSphere, 2018-12-05;3(6):.  2018-12-05
  33. Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles
    Authors: P Sykora, Y Chiari, A Heaton, N Moreno, S Glaberman, RW Sobol
    Environ. Mol. Mutagen., 2018-03-14;0(0):.  2018-03-14
  34. Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture.
    Authors: Liu F, Patterson T, Sadovova N, Zhang X, Liu S, Zou X, Hanig J, Paule M, Slikker W, Wang C
    Toxicol Sci, 2012-10-11;131(2):548-57.  2012-10-11
  35. Radioprotective properties of tocopherol succinate against ionizing radiation in mice.
    Authors: Singh V, Singh P, Wise S, Posarac A, Fatanmi O
    J Radiat Res, 2012-10-03;54(2):210-20.  2012-10-03
  36. Nongenotoxic apoptosis inducers do not produce misleading positive results in the TK6 cell-based GADD45a-GFP genotoxicity assay.
    Authors: Topham C, Billinton N, Walmsley R
    Toxicol Sci, 2012-04-05;128(1):79-91.  2012-04-05
  37. Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors.
    Authors: Lee J, Choy M, Ngo L, Venta-Perez G, Marks P
    Proc Natl Acad Sci U S A, 2011-11-21;108(49):19629-34.  2011-11-21

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CometAssay Lysis Solution
By Anonymous on 05/16/2018