CometAssay Lysis Solution

100 mL and 1000 mL (2 x 500 mL) available
Catalog # Availability Size / Price Qty
4250-010-01
4250-050-01
Product Details
Citations (25)
FAQs
Reviews (1)

CometAssay Lysis Solution Summary

CometAssay Lysis Solution contains high salt and detergent and is suitable for use with either the alkaline or neutral comet assay protocol. 

Available as 100 mL or 1000 mL (2 x 500 mL) volumes.
 

Key Benefits

• Designed for use with CometAssay, FLARE, and CometChip.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended on the label.
Storage
Store the unopened product at room temperature. Do not use past expiration date.
Species
N/A

Limitations

For research use only. Not for diagnostic use.

Product Datasheets

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Citations for CometAssay Lysis Solution

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

25 Citations: Showing 1 - 10
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  1. Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
    Authors: J Li, CA Koczor, KM Saville, F Hayat, A Beiser, S McClellan, ME Migaud, RW Sobol
    Cancers, 2022;14(15):.  2022
  2. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
    Authors: M Yoshinaga, K Han, DW Morgens, T Horii, R Kobayashi, T Tsuruyama, F Hia, S Yasukura, A Kajiya, T Cai, PHC Cruz, A Vandenbon, Y Suzuki, Y Kawahara, I Hatada, MC Bassik, O Takeuchi
    Nature Communications, 2022;13(1):6435.  2022
  3. Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
    Authors: FB Rashed, D Diaz-Dussa, F Mashayekhi, D Macdonald, PN Nation, XH Yang, S Sokhi, AC Stoica, H El-Saidi, C Ricardo, R Narain, IH Ismail, LI Wiebe, P Kumar, M Weinfeld
    Redox Biology, 2022;52(0):102300.  2022
  4. Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor
    Authors: B Jiang, C Murray, BL Cole, JNM Glover, GK Chan, J Deschenes, RS Mani, S Subedi, JD Nerva, AC Wang, CM Lockwood, HC Mefford, SES Leary, JG Ojemann, M Weinfeld, CI Ene
    Scientific Reports, 2022;12(1):5386.  2022
  5. Evaluation of phototoxicity induced by the anticancer drug rucaparib
    Authors: A Mateos-Puj, MC Jiménez, I Andreu
    Scientific Reports, 2022;12(1):3434.  2022
  6. Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage
    Authors: X Wu, B Wang
    Nature Communications, 2021;12(1):4373.  2021
  7. Performance Evaluation for Repair of HSGc-C5 Carcinoma Cell Using Geant4-DNA
    Authors: D Sakata, M Suzuki, R Hirayama, Y Abe, M Muramatsu, S Sato, O Belov, I Kyriakou, D Emfietzogl, S Guatelli, S Incerti, T Inaniwa
    Cancers, 2021;13(23):.  2021
  8. Genetic vulnerabilities upon inhibition of DNA damage response
    Authors: C Wang, M Tang, Z Chen, L Nie, S Li, Y Xiong, KA Szymonowic, JM Park, H Zhang, X Feng, M Huang, D Su, T Hart, J Chen
    Nucleic Acids Research, 2021;0(0):.  2021
  9. DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation
    Authors: W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ZM Zhang, JP Coan, J Yin, DI Kim, L Gao, L Cai, N Khudaverdy, B Çetin, DJ Patel, Y Wang, Q Cui, BD Strahl, O Gozani, KM Miller, SE O'Leary, PA Wade, GG Wang, J Song
    Nature Communications, 2021;12(1):2490.  2021
  10. Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors
    Authors: E Grimley, AJ Cole, TT Luong, SC McGonigal, S Sinno, D Yang, KA Bernstein, RJ Buckanovic
    Theranostics, 2021;11(8):3540-3551.  2021
  11. Super-resolution visualization of distinct stalled and broken replication fork structures
    Authors: DR Whelan, WTC Lee, F Marks, YT Kong, Y Yin, E Rothenberg
    PloS Genetics, 2020;16(12):e1009256.  2020
  12. Fanconi Anemia Pathway Activation by FOXM1 Is Critical to Bladder Cancer Recurrence and Anticancer Drug Resistance
    Authors: YG Roh, JY Mun, SK Kim, W Park, MS Jeong, TN Kim, WT Kim, YH Choi, IS Chu, SH Leem
    Cancers (Basel), 2020;12(6):.  2020
  13. Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
    Authors: FA Alhumaydhi, D de O Lopes, DL Bordin, ASM Aljohani, CB Lloyd, MD McNicholas, L Milano, CF Charlier, I Villela, JAP Henriques, KE Plant, RM Elliott, LB Meira
    Sci Rep, 2020;10(1):2209.  2020
  14. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
    Authors: X Meng, Y Zhao, B Han, C Zha, Y Zhang, Z Li, P Wu, T Qi, C Jiang, Y Liu, J Cai
    Nat Commun, 2020;11(1):594.  2020
  15. Karyopherin &alpha-2 Mediates MDC1 Nuclear Import through a Functional Nuclear Localization Signal in the tBRCT Domain of MDC1
    Authors: K Radhakrish, SJ Park, SW Kim, G Hariharasu, SY Jeong, IY Chang, JH Lee
    Int J Mol Sci, 2020;21(7):.  2020
  16. Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS
    Authors: JAG Agúndez, E García-Mar, G García-Lai, MA Miranda, I Andreu
    Sci Rep, 2020;10(1):6879.  2020
  17. A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells
    Authors: M Wakita, A Takahashi, O Sano, TM Loo, Y Imai, M Narukawa, H Iwata, T Matsudaira, S Kawamoto, N Ohtani, T Yoshimori, E Hara
    Nat Commun, 2020;11(1):1935.  2020
  18. Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro
    Authors: KJ Nytko, P Thumser-He, MS Weyland, S Scheidegge, CR Bley
    PLoS ONE, 2019;14(5):e0216744.  2019
  19. CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs
    Authors: M Mohiuddin, MM Rahman, JE Sale, CE Pearson
    Nucleic Acids Res., 2019;0(0):.  2019
  20. Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles
    Authors: P Sykora, Y Chiari, A Heaton, N Moreno, S Glaberman, RW Sobol
    Environ. Mol. Mutagen., 2018;0(0):.  2018
  21. Marginal Zinc Deficiency and Environmentally Relevant Concentrations of Arsenic Elicit Combined Effects on the Gut Microbiome
    Authors: CA Gaulke, J Rolshoven, CP Wong, LG Hudson, E Ho, TJ Sharpton
    mSphere, 2018;3(6):.  2018
  22. Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors.
    Authors: Lee J, Choy M, Ngo L, Venta-Perez G, Marks P
    Proc Natl Acad Sci U S A, 0;108(49):19629-34.  0
  23. Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture.
    Authors: Liu F, Patterson T, Sadovova N, Zhang X, Liu S, Zou X, Hanig J, Paule M, Slikker W, Wang C
    Toxicol Sci, 0;131(2):548-57.  0
  24. Nongenotoxic apoptosis inducers do not produce misleading positive results in the TK6 cell-based GADD45a-GFP genotoxicity assay.
    Authors: Topham C, Billinton N, Walmsley R
    Toxicol Sci, 0;128(1):79-91.  0
  25. Radioprotective properties of tocopherol succinate against ionizing radiation in mice.
    Authors: Singh V, Singh P, Wise S, Posarac A, Fatanmi O
    J Radiat Res, 0;54(2):210-20.  0

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CometAssay Lysis Solution
By Anonymous on 05/16/2018