CometSlide High Throughput
CometSlide High Throughput Summary
Why Use CometSlides for the CometAssay?
CometSlide High Throughput is a component of the CometAssay High Throughput Kit (R&D Systems®, Catalog # 4252-040-K) which is used for the rapid analysis of DNA fragmentation associated with DNA damage. CometSlide High Throughput is a 20-well slide that is specially treated to promote agarose adherence and easy application of cells directly to each well. This slide provides a convenient, simple, and reliable format for sample preparation, processing, analysis, and storage for the CometAssay.
The CometAssay, or single cell gel electrophoresis assay, permits the quantification of DNA damage in individual cells based on the migration of DNA structures in an electric field. Evaluation of the DNA “Comet” tail shape and migration pattern allows for assessment of DNA damage, expressed as tail length, percent DNA in the tail and tail moment.
For research use only. Not for diagnostic use.
Citations for CometSlide High Throughput
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus
Authors: I Rashid, M Hammel, A Sverzhinsk, MS Tsai, JM Pascal, JA Tainer, AE Tomkinson
The Journal of Biological Chemistry, 2021;0(0):100921. 2021
Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China
Authors: S Chen, D Li, X Wu, L Chen, B Zhang, Y Tan, D Yu, Y Niu, H Duan, Q Li, R Chen, M Aschner, Y Zheng, W Chen
Environ Int, 2020;139(0):105703. 2020
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