Complement C8A Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47462

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Complement C8A Primary Antibodies »

Product Specifications

Immunogen

Complement component C8 alpha chain. (Uniprot# P07357)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Complement C8A Antibody - BSA Free

Complement C8A Antibody - BSA Free

Immunohistochemistry: Complement C8A Antibody - BSA Free [NBP3-47462] -

Immunohistochemistry: Complement C8A Antibody - BSA Free [NBP3-47462] - Immunohistochemistry of paraffin-embedded Rat liver tissue slide using (Complement C8A antibody) at dilution of 1:200

Applications for Complement C8A Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:500

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Complement C8A

C8 is synthesised in the liver, monocytes and fibroblasts and is a plasma protein consisting of three non identical polypeptide chains. The alpha-chain (64kDa) and gamma chain (22kDa) are disulphide linked, these associate non-covalently with the beta-chain (64kDa), to form the native C8 molecule with a molecular weight of 151kDa. Normal plasma concentration is 80mg/L.C8 is one of the terminal proteins of the complement pathways. C8 binds to the membrane bound C5b-7, C5b-8 combines with C9 to form the membrane attack complex (MAC). The MAC forms a hydrophilic, protein walled, transmembrane channel, formation of which leads to cell lysis and destruction.

Alternate Names

complement component 8, alpha polypeptide, complement component C8 alpha chain

Gene Symbol

C8A

Additional Complement C8A Products

Product Documents for Complement C8A Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Complement C8A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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