CRM1 Antibody (9F2) - BSA Free

Novus Biologicals | Catalog # NBP3-26249

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 9F2 expressed in HEK293

Format

BSA Free
View all CRM1 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human CRM1 [UniProt O14980]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRM1 Antibody (9F2) - BSA Free

CRM1 Antibody (9F2)

Immunohistochemistry: CRM1 Antibody (9F2) [NBP3-26249] -

Immunohistochemistry: CRM1 Antibody (9F2) [NBP3-26249] - Image of CRM1 Antibody (9F2) diluted at 1:100 and staining in paraffin-embedded human ovarian tissue performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
CRM1 Antibody (9F2)

Immunohistochemistry: CRM1 Antibody (9F2) [NBP3-26249] -

Immunohistochemistry: CRM1 Antibody (9F2) [NBP3-26249] - Image of CRM1 Antibody (9F2) diluted at 1:100 and staining in paraffin-embedded human ovarian tissue performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Applications for CRM1 Antibody (9F2) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, and 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: CRM1

Official Gene Symbol: XPO1 Gen Bank Accession Number: NP_003391 Gene ID: 7514 (human) Gene Map Locus: 2p16 (human) Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-1, a human homolog of yeast CRM1, is a novel karyopherin export receptor that mediates leucine-rich NES-dependent protein export. It interacts with RanGTP through its Ran-binding domain and also with nucleoporins including Nup214, Nup50, Nup42 and Nup159 during the process of exporting NES-containing proteins. It mediates the export of many cellular and viral proteins and ribonucleoproteins including HIV Rev Protein, ERK3, PKI, IRF-5, Cyclin-B, MAPKK, MAPKAP kinase 2, Snurportin, Cap-binding protein, and certain U snRNAs. Reports suggest exportin-1 also has a role in the regulation of NFAT and AP-1.

Long Name

Chromosome Region Maintenence 1 Homolog

Alternate Names

CRM-1, Exp1, Exportin 1, XPO1

Gene Symbol

XPO1

Additional CRM1 Products

Product Documents for CRM1 Antibody (9F2) - BSA Free

Certificate of Analysis

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Product Specific Notices for CRM1 Antibody (9F2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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