Cultrex Mouse Laminin I, Pathclear

Mouse Laminin I purified and qualified for use in cell culture
Catalog # Availability Size / Price Qty
3400-010-02
Product Details
Citations (19)
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Cultrex Mouse Laminin I, Pathclear Summary

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended on the product label.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Citations for Cultrex Mouse Laminin I, Pathclear

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

19 Citations: Showing 1 - 10
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  1. 2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer
    Authors: Coy, S;Cheng, B;Lee, JS;Rashid, R;Browning, L;Xu, Y;Chakrabarty, SS;Yapp, C;Chan, S;Tefft, JB;Scott, E;Spektor, A;Ligon, KL;Baker, GJ;Pellman, D;Sorger, PK;Santagata, S;
    bioRxiv : the preprint server for biology  2023-11-11
  2. Stressed neuronal cells can recover from profound membrane blebbing, nuclear condensation and mitochondrial fragmentation, but not from cytochrome c release
    Authors: You, W;Zhou, T;Knoops, K;Berendschot, TTJM;van Zandvoort, MAMJ;Germeraad, WTV;Benedikter, B;Webers, CAB;Reutelingsperger, CPM;Gorgels, TGMF;
    Scientific reports  2023-07-08
  3. In vitro myelination using explant culture of dorsal root ganglia: An efficient tool for analyzing peripheral nerve differentiation and disease modeling
    Authors: Numata-Uematasu, Y;Wakatsuki, S;Kobayashi-Ujiie, Y;Sakai, K;Ichinohe, N;Araki, T;
    PloS one  2023-05-24
  4. Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma
    Authors: RM Samuel, A Navickas, A Maynard, EA Gaylord, K Garcia, S Bhat, H Majd, MN Richter, N Elder, D Le, P Nguyen, B Shibata, ML Llabata, L Selleri, DJ Laird, S Darmanis, H Goodarzi, F Fattahi
    bioRxiv : the preprint server for biology, 2023-03-07;0(0):.  2023-03-07
  5. Drug Resistance in Medulloblastoma Is Driven by YB-1, ABCB1 and a Seven-Gene Drug Signature
    Authors: L Taylor, PK Wade, JEC Johnson, M Aldighieri, S Morlando, G Di Leva, ID Kerr, B Coyle
    Cancers, 2023-02-08;15(4):.  2023-02-08
  6. Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2
    Authors: JH Pham, GA Johnson, RS Rangan, CE Amankwa, S Acharya, DL Stankowska
    Cells, 2022-11-23;11(23):.  2022-11-23
  7. Single Cell Analysis of Reversibility of the Cell Death Program in Ethanol-Treated Neuronal PC12 Cells
    Authors: W You, TTJM Berendscho, K Knoops, MAMJ van Zandvo, CAB Webers, CPM Reutelings, TGMF Gorgels
    International Journal of Molecular Sciences, 2022-02-28;23(5):.  2022-02-28
  8. Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function
    Authors: P Schiappare, NL Pirman, K Mohler, PA Miranda-He, N Zarco, O Kilic, C Miller, SR Shah, S Rogulina, W Hungerford, L Abriola, D Hoyer, BE Turk, H Guerrero-C, FJ Isaacs, A Quiñones-H, A Levchenko, J Rinehart
    Cell Reports, 2021-07-20;36(3):109416.  2021-07-20
  9. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01
    Authors: J Piao, S Zabierowsk, BN Dubose, EJ Hill, M Navare, N Claros, S Rosen, K Ramnarine, C Horn, C Fredrickso, K Wong, B Safford, S Kriks, A El Maarouf, U Rutishause, C Henchcliff, Y Wang, I Riviere, S Mann, V Bermudez, S Irion, L Studer, M Tomishima, V Tabar
    Cell Stem Cell, 2021-02-04;28(2):217-229.e7.  2021-02-04
  10. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020-06-19;27(1):125-136.e7.  2020-06-19
  11. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020;27(1):125-136.e7.  2020
  12. Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control
    Authors: S Ghatak, N Dolatabadi, D Trudler, X Zhang, Y Wu, M Mohata, R Ambasudhan, M Talantova, SA Lipton
    Elife, 2019-11-29;8(0):.  2019-11-29
  13. The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor
    Authors: JM Aye, LL Stafman, AP Williams, EF Garner, JE Stewart, JC Anderson, S Mruthyunja, MG Waldrop, CD Goolsby, HR Markert, C Quinn, R Marayati, E Mroczek-Mu, CD Willey, KJ Yoon, KF Whelan, EA Beierle
    Oncotarget, 2019-09-17;10(53):5534-5548.  2019-09-17
  14. Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts
    Authors: LL Stafman, AP Williams, R Marayati, JM Aye, HR Markert, EF Garner, CH Quinn, SB Lallani, JE Stewart, KJ Yoon, K Whelan, EA Beierle
    Sci Rep, 2019-09-13;9(1):13259.  2019-09-13
  15. A cell fitness selection model for neuronal survival during development
    Authors: Y Wang, H Wu, P Fontanet, S Codeluppi, N Akkuratova, C Petitpré, Y Xue-Franzé, K Niederreit, A Sharma, F Da Silva, G Comai, G Agirman, D Palumberi, S Linnarsson, I Adameyko, A Moqrich, A Schedl, G La Manno, S Hadjab, F Lallemend
    Nat Commun, 2019-09-12;10(1):4137.  2019-09-12
  16. Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons
    Authors: RO Costa, H Martins, LF Martins, AW Cwetsch, M Mele, JR Pedro, D Tomé, NL Jeon, L Cancedda, SR Jaffrey, RD Almeida
    Cell Rep, 2019-07-23;28(4):864-876.e6.  2019-07-23
  17. Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity
    Authors: M Plataki, L Fan, E Sanchez, Z Huang, LK Torres, M Imamura, Y Zhu, DE Cohen, SM Cloonan, AM Choi
    JCI Insight, 2019-07-09;5(0):.  2019-07-09
  18. Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
    Authors: A Ordureau, JA Paulo, W Zhang, T Ahfeldt, J Zhang, EF Cohn, Z Hou, JM Heo, LL Rubin, SS Sidhu, SP Gygi, JW Harper
    Mol. Cell, 2018-04-12;70(2):211-227.e8.  2018-04-12
  19. Amacrine cell subtypes differ in their intrinsic neurite growth capacity.
    Authors: Kunzevitzky N, Willeford K, Feuer W, Almeida M, Goldberg J
    Invest Ophthalmol Vis Sci, 2013-11-15;54(12):7603-13.  2013-11-15

FAQs

  1. What is the recommended working concentration for Cultrex Laminin I?

    • The recommended working concentration for thin coating is 0.05-10 µg/cm2 . However, conditions must be optimized for each cell line or model. Cultrex Laminin I should be used at 6 mg/mL for 3-D culture applications.

       

  2. What is Laminin I?

    • Laminin I is a major component of extracellular matrix. Cultrex Laminin I is purified from murine EHS sarcoma. It is composed of α1β1γ1 chains with a total MW of 800,000 Da. Cultrex Laminin I increases cell adhesion, migration, growth, differentiation, neurite outgrowth, protease production, and malignancy. The response is dependent on cell type.

  3. Can Cultrex Mouse Laminin I be used on glass cover slips?

    • Coating glass cover slips with Cultrex Laminin I is quite common and has been published extensively.

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