Cultrex Poly-L-Lysine

Poly-amino solution that promotes cell adhesion
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Product Details
Citations (17)
Reviews (1)

Cultrex Poly-L-Lysine Summary

Cultrex Poly-L-Lysine is a poly-amino acid solution that is provided ready to use at a concentration 0.01%.

Key Benefits

• Promotes the proliferation and differentiation of a variety of neuronal cell lines
• Facilitates cell adhesion on tissue culture-treated plastic or glass surfaces
• Contains polymers in the 70,000-150,000 Da range
• Provided in phosphate-buffered saline (PBS)

Why Use Cultrex Poly-L-Lysine?

Poly-L-Lysine, a highly positively charged synthetic amino acid chain, is commonly used as a coating agent to promote cell adhesion in culture on tissue culture-treated plastic or glass surfaces. Moreover, poly-L-Lysine contains polymers in the 70,000-150,000 Da range and promotes the proliferation and differentiation of a variety of neuronal cell lines. This solution is provided sterile filtered and ready to use at 0.01%.


Protein Concentration
0.1 mg/mL
Endotoxin Level
≤ 20 EU/mL by Limulus Amoebocyte Lysate (LAL) assay
Sterility Testing
No bacterial or fungal growth detected following 14 days in culture
Testing Cell Culture
Supports attachment of rat PC-12 pheochromocytoma cells.
Product is stable for at least 3 months from the date of receipt when stored at 2-8 °C. Keep sterile.
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Store the unopened product at 2 - 8 °C.


For research use only. Not for diagnostic use.

Product Datasheets

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Citations for Cultrex Poly-L-Lysine

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

17 Citations: Showing 1 - 10
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  1. Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
    Authors: Dimou, E;Katsinelos, T;Meisl, G;Tuck, BJ;Keeling, S;Smith, AE;Hidari, E;Lam, JYL;Burke, M;Lövestam, S;Ranasinghe, RT;McEwan, WA;Klenerman, D;
    Cell reports  2023-07-01
  2. Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma
    Authors: J Lehmann, N Caduff, E Krzywi?ska, S Stierli, A Salas-Bast, B Loos, MP Levesque, R Dummer, C Stockmann, C Münz, J Diener, L Sommer
    Science Advances, 2023-01-13;9(2):eadc8825.  2023-01-13
  3. Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells
    Authors: T Hattori, T Saito, H Miyamoto, M Kajihara, M Igarashi, A Takada
    Viruses, 2022-09-26;14(10):.  2022-09-26
  4. Residues in the 1st Transmembrane-Spanning Helix Are Important for GABAA? Receptor Function
    Authors: KM Crowther, SM Mesoy, SCR Lummis
    Biomolecules, 2022-09-07;12(9):.  2022-09-07
  5. Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus
    Authors: T Saito, T Hattori, K Okuya, R Manzoor, H Miyamoto, M Kajihara, A Takada
    MBio, 2022-02-15;0(0):e0306021.  2022-02-15
  6. Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation
    Authors: E Dobosz, G Lorenz, A Ribeiro, V Würf, M Wadowska, J Kotlinowsk, C Schmaderer, J Potempa, M Fu, J Koziel, M Lech
    Disease Models & Mechanisms, 2021-03-18;14(3):.  2021-03-18
  7. Purification of Crimean-Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis
    Authors: BP Lombe, H Miyamoto, T Saito, R Yoshida, R Manzoor, M Kajihara, M Shimojima, S Fukushi, S Morikawa, T Yoshikawa, T Kurosu, M Saijo, Q Tang, J Masumu, D Hawman, H Feldmann, A Takada
    Scientific Reports, 2021-01-27;11(1):2324.  2021-01-27
  8. c-Rel gain in B cells drives germinal center reactions and autoantibody production
    Authors: M Kober-Hass, H Oh-Strau beta, D Kumar, V Soberón, C Diehl, M Lech, T Engleitner, E Katab, V Fernandez, G Piontek, H Li, B Menze, C Ziegenhain, W Enard, R Rad, JP Böttcher, HJ Anders, M Rudelius, M Schmidt-Su
    J. Clin. Invest., 2020-06-01;0(0):.  2020-06-01
  9. Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport.
    Authors: Pahwa S, Alam K, Crowe A, Farasyn T, Neuhoff S, Hatley O, Ding K, Yue W
    J Pharm Sci, 2017-04-01;106(8):2123-2135.  2017-04-01
  10. Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs.
    Authors: McLean W, McLean D, Eatock R, Edge A
    Development, 2016-10-27;143(23):4381-4393.  2016-10-27
  11. JAZ (Znf346), a SIRT1-interacting protein, protects neurons by stimulating p21 (WAF/CIP1) protein expression.
    Authors: Mallick S, D'Mello S
    J Biol Chem, 2014-10-20;289(51):35409-20.  2014-10-20
  12. NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents.
    Authors: Harkcom W, Ghosh A, Sung M, Matov A, Brown K, Giannakakou P, Jaffrey S
    Proc Natl Acad Sci U S A, 2014-06-02;111(24):E2443-52.  2014-06-02
  13. Effects of ethanol on glycinergic synaptic currents in mouse spinal cord neurons.
    Authors: Mariqueo T, Agurto A, Munoz B, San Martin L, Coronado C, Fernandez-Perez E, Murath P, Sanchez A, Homanics G, Aguayo L
    J Neurophysiol, 2014-02-26;111(10):1940-8.  2014-02-26
  14. HSF1 protects neurons through a novel trimerization- and HSP-independent mechanism.
    Authors: Verma P, Pfister J, Mallick S, D'Mello S
    J Neurosci, 2014-01-29;34(5):1599-612.  2014-01-29
  15. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG.
    Authors: Walker B, Ji S, Jaffrey S
    J Neurosci, 2012-10-10;32(41):14442-7.  2012-10-10
  16. Recombinant chaperonin 10 suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice.
    Authors: Kulkarni O, Ryu M, Kantner C, Sardy M, Naylor D, Lambert D, Brown R, Anders H
    Nephrol Dial Transplant, 2011-10-10;27(4):1358-67.  2011-10-10
  17. Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
    Authors: Lech M, Kantner C, Kulkarni O, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Kobayashi K, Flavell R, Martin J, Anders H
    Ann Rheum Dis, 2011-08-29;70(12):2207-17.  2011-08-29


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Cultrex Poly-L-Lysine
By Anonymous on 03/23/2018
Application: Media additive for protein or antibody production