Cultrex Poly-L-Lysine

Poly-amino solution that promotes cell adhesion
Catalog # Availability Size / Price Qty

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Product Details
Citations (13)
Reviews (1)

Cultrex Poly-L-Lysine Summary

Cultrex Poly-L-Lysine is a poly-amino acid solution that is provided ready to use at a concentration 0.01%.

Key Benefits

• Promotes the proliferation and differentiation of a variety of neuronal cell lines
• Facilitates cell adhesion on tissue culture-treated plastic or glass surfaces
• Contains polymers in the 70,000-150,000 Da range
• Provided in phosphate-buffered saline (PBS)

Why Use Cultrex Poly-L-Lysine?

Poly-L-Lysine, a highly positively charged synthetic amino acid chain, is commonly used as a coating agent to promote cell adhesion in culture on tissue culture-treated plastic or glass surfaces. Moreover, poly-L-Lysine contains polymers in the 70,000-150,000 Da range and promotes the proliferation and differentiation of a variety of neuronal cell lines. This solution is provided sterile filtered and ready to use at 0.01%.


Protein Concentration
0.1 mg/mL
Endotoxin Level
≤ 20 EU/mL by Limulus Amoebocyte Lysate (LAL) assay
Sterility Testing
No bacterial or fungal growth detected following 14 days in culture
Testing Cell Culture
Supports attachment of rat PC-12 pheochromocytoma cells.
Product is stable for at least 3 months from the date of receipt when stored at 2-8 °C. Keep sterile.
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Store the unopened product at 2 - 8 °C.


For research use only. Not for diagnostic use.

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Citations for Cultrex Poly-L-Lysine

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

13 Citations: Showing 1 - 10
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  1. Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus
    Authors: T Saito, T Hattori, K Okuya, R Manzoor, H Miyamoto, M Kajihara, A Takada
    MBio, 2022;0(0):e0306021.  2022
  2. Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation
    Authors: E Dobosz, G Lorenz, A Ribeiro, V Würf, M Wadowska, J Kotlinowsk, C Schmaderer, J Potempa, M Fu, J Koziel, M Lech
    Disease Models & Mechanisms, 2021;14(3):.  2021
  3. Purification of Crimean-Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis
    Authors: BP Lombe, H Miyamoto, T Saito, R Yoshida, R Manzoor, M Kajihara, M Shimojima, S Fukushi, S Morikawa, T Yoshikawa, T Kurosu, M Saijo, Q Tang, J Masumu, D Hawman, H Feldmann, A Takada
    Scientific Reports, 2021;11(1):2324.  2021
  4. c-Rel gain in B cells drives germinal center reactions and autoantibody production
    Authors: M Kober-Hass, H Oh-Strau beta, D Kumar, V Soberón, C Diehl, M Lech, T Engleitner, E Katab, V Fernandez, G Piontek, H Li, B Menze, C Ziegenhain, W Enard, R Rad, JP Böttcher, HJ Anders, M Rudelius, M Schmidt-Su
    J. Clin. Invest., 2020;0(0):.  2020
  5. Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport.
    Authors: Pahwa S, Alam K, Crowe A, Farasyn T, Neuhoff S, Hatley O, Ding K, Yue W
    J Pharm Sci, 0;106(8):2123-2135.  0
  6. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG.
    Authors: Walker B, Ji S, Jaffrey S
    J Neurosci, 0;32(41):14442-7.  0
  7. JAZ (Znf346), a SIRT1-interacting protein, protects neurons by stimulating p21 (WAF/CIP1) protein expression.
    Authors: Mallick S, D'Mello S
    J Biol Chem, 0;289(51):35409-20.  0
  8. Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs.
    Authors: McLean W, McLean D, Eatock R, Edge A
    Development, 0;143(23):4381-4393.  0
  9. Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
    Authors: Lech M, Kantner C, Kulkarni O, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Kobayashi K, Flavell R, Martin J, Anders H
    Ann Rheum Dis, 0;70(12):2207-17.  0
  10. Recombinant chaperonin 10 suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice.
    Authors: Kulkarni O, Ryu M, Kantner C, Sardy M, Naylor D, Lambert D, Brown R, Anders H
    Nephrol Dial Transplant, 0;27(4):1358-67.  0
  11. HSF1 protects neurons through a novel trimerization- and HSP-independent mechanism.
    Authors: Verma P, Pfister J, Mallick S, D'Mello S
    J Neurosci, 0;34(5):1599-612.  0
  12. NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents.
    Authors: Harkcom W, Ghosh A, Sung M, Matov A, Brown K, Giannakakou P, Jaffrey S
    Proc Natl Acad Sci U S A, 0;111(24):E2443-52.  0
  13. Effects of ethanol on glycinergic synaptic currents in mouse spinal cord neurons.
    Authors: Mariqueo T, Agurto A, Munoz B, San Martin L, Coronado C, Fernandez-Perez E, Murath P, Sanchez A, Homanics G, Aguayo L
    J Neurophysiol, 0;111(10):1940-8.  0


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Cultrex Poly-L-Lysine
By Anonymous on 03/23/2018
Application: Media additive for protein or antibody production