CXCL10/IP-10 is an ELR- angiostatic chemokine that interacts with CXCR3 to attract Th1 cells, eosinophils, monocytes, and NK cells to sites of inflammation. It is upregulated by activated T lymphocytes, neutrophils, splenocytes, keratinocytes, osteoblasts, astrocytes, endothelial cells, smooth muscle cells, and pancreatic beta cells. CXCL10 contributes to disease pathology in many chronic inflammatory disorders including rheumatoid arthritis, psoriasis, cancer, multiple sclerosis, diabetes, and cardiovascular disease.
Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein
Novus Biologicals | Catalog # NBP2-62477
Key Product Details
Source
Accession Number
Applications
Product Specifications
Description
Source:Pichia pastoris
Amino Acid Sequence:aa 22 - 98 of native rabbit IP-10.
Purity
Predicted Molecular Mass
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Protein / Peptide Type
Scientific Data Images for Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein
ELISA: Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein [NBP2-62477] -
ELISA: Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein [NBP2-62477] - Rabbit IP-10 ELISARecombinant Rabbit IP-10detected using Goat anti Rabbit IP-10 as the capture reagent and Goat anti Rabbit IP-10:Biotin as the detection reagent followed by Streptavidin:HRP.
Formulation, Preparation, and Storage
NBP2-62477
| Preparation Method | Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography. |
| Formulation | PBS |
| Preservative | 10% Trehalose |
| Concentration | Lyoph |
| Reconstitution | Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution. |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20C. Avoid freeze-thaw cycles. |
Calculators
Background: CXCL10/IP-10/CRG-2
Additional CXCL10/IP-10/CRG-2 Products
Product Documents for Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Recombinant Rabbit CXCL10/IP-10/CRG-2 Protein
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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