CXCR2/IL-8RB Antibody (HC2) [Alexa Fluor™ Plus 647] - Chimeric

Novus Biologicals | Catalog # NBP3-12005AFP647

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Alexa Fluor Plus 647

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # HC2
View all CXCR2/IL-8RB Primary Antibodies »

Product Specifications

Immunogen

This antibody was raised by immunizing mice with human IL-8 (interleukin-8) receptor, type B.

Specificity

HC2 recognizes human C-X-C chemokine receptor type 2, (CXCR2). CD182 is a 360 amino acid multipass membrane glcycoprotein and is expressed by neutrophils and monocytes, as well as by some subsets of T cells and endothelial cells.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for CXCR2/IL-8RB Antibody (HC2) [Alexa Fluor™ Plus 647] - Chimeric

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCR2/IL-8RB

Chemokine (Chemoattractant Cytokines) are small peptides that are potent activators and chemo-attractants for leukocyte subpopulations and other non-hemopoietic cells. Chemokine receptors (CXCR) belong to the super-family of G protein-coupled receptors (GPCR), which regulate the trafficking and activation of leukocytes, and operate as co-receptors in the entry of HIV-1 and proliferation and migration of immature neurons, glia and their precursors. Furthermore, chemokine receptors participate in the etiology and progression of various brain disorders, including AIDS dementia, neuro-inflammatory disease and neuroplasia, making them important potential therapeutic targets in these cases several subtypes of CXCR have been characterized. Activation of na

Long Name

Interleukin 8 Receptor B

Alternate Names

CD182, CDw128b, CMKAR2, CXCR-2, IL-8 RB, IL8RB

Gene Symbol

CXCR2

Additional CXCR2/IL-8RB Products

Product Documents for CXCR2/IL-8RB Antibody (HC2) [Alexa Fluor™ Plus 647] - Chimeric

Certificate of Analysis

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Product Specific Notices for CXCR2/IL-8RB Antibody (HC2) [Alexa Fluor™ Plus 647] - Chimeric



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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