Cyclopiazonic acid

  ( 10 citations )    
Product Datasheet
Catalog Number:1235
Alternate Names:α-Cyclopiazonic acid
Chemical Name:(6aR,11aS,11bR)-rel-10-Acetyl-2,6,6a,7,11a,11b-hexahydro-7,7-dimethyl-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one
Product Details
Citations (10)
Biological Activity
Cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 5 mM in ethanol with gentle warming and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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The citations listed below are publications that use Tocris products. Selected citations for Cyclopiazonic acid include:

10 Citations: Showing 1 - 10
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  1. Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion.
    Authors: Li Et al.
    Cell Death Dis  2016;7:e2275
  2. Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells.
    Authors: Elgueta Et al.
    Neuropharmacology  2015;9:6
  3. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.
    Authors: Fransen Et al.
    J Neurosci  2015;10:e0121634
  4. Hippocampal Gαq/11 but not Gαo-coupled receptors are altered in aging.
    Authors: McQuail Et al.
    Cardiovasc Res  2013;70:63
  5. Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.
    Authors: Alzayady Et al.
    J Biol Chem  2013;288:11122
  6. Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.
    Authors: Earls Et al.
    Front Cell Neurosci  2010;30:15843
  7. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.
    Authors: Grey and Burrell
    J Neurophysiol  2010;103:2737
  8. Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
    Authors: Choi Et al.
    PLoS One  2009;82:324
  9. Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients.
    Authors: Eder and Bading
    BMC Neurosci  2007;8:57
  10. Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores.
    Authors: Kumar and Foster
    J Neurophysiol  2004;91:2437


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