Cyclopiazonic acid

  ( 10 citations )    
Product Datasheet
Catalog Number:1235
Alternate Names:α-Cyclopiazonic acid
Chemical Name:(6aR,11aS,11bR)-rel-10-Acetyl-2,6,6a,7,11a,11b-hexahydro-7,7-dimethyl-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one
Product Details
Citations (10)
Reviews
Biological Activity
Cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase.
Technical Data
  • M.Wt:
    336.39
  • Formula:
    C20H20N2O3
  • Solubility:
    Soluble to 5 mM in ethanol with gentle warming and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    18172-33-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cyclopiazonic acid include:

10 Citations: Showing 1 - 10
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  1. Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion.
    Authors: Li Et al.
    Cell Death Dis  2016;7:e2275
  2. Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells.
    Authors: Elgueta Et al.
    Neuropharmacology  2015;9:6
  3. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.
    Authors: Fransen Et al.
    J Neurosci  2015;10:e0121634
  4. Hippocampal Gαq/11 but not Gαo-coupled receptors are altered in aging.
    Authors: McQuail Et al.
    Cardiovasc Res  2013;70:63
  5. Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.
    Authors: Alzayady Et al.
    J Biol Chem  2013;288:11122
  6. Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.
    Authors: Earls Et al.
    Front Cell Neurosci  2010;30:15843
  7. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.
    Authors: Grey and Burrell
    J Neurophysiol  2010;103:2737
  8. Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
    Authors: Choi Et al.
    PLoS One  2009;82:324
  9. Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients.
    Authors: Eder and Bading
    BMC Neurosci  2007;8:57
  10. Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores.
    Authors: Kumar and Foster
    J Neurophysiol  2004;91:2437

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