Catalog Number: 0213
Chemical Name: D-Aminosuccinic acid
Biological Activity
Endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.

L-isomer also available.

Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Free D-aspartate and D-serine in the mammalian brain and periphery.
    Hashimoto et al.
    Prog.Neurobiol., 1997;53:325
  2. D-Aspartate modulates melatonin synthesis in rat pinealocytes.
    Ishio et al.
    Neurosci.Lett., 1998;249:143
  3. Structure/activity relations of NMDA receptor ligands as studied by their inhibition of 3H-D-AP5 binding in rat brain membranes.
    Olverman et al.
    Neuroscience, 1988;26:17

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