Decynium 22
Discontinued Product
Chemical Name: 1-Ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]quinolinium iodide
Purity: ≥98%
Biological Activity
Decynium 22 is an inhibitor of the plasma membrane monoamine transporter (PMAT) (Ki = 0.10 μM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Interaction of organic cations with a newly identified plasma membrane monoamine transporter.
Engel and Wang
Mol.Pharmacol., 2005;68:1397 -
Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity.
Xia et al.
Am.J.Physiol.Renal Physiol., 2009;296:F1307
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Citation for Decynium 22
The citations listed below are publications that use Tocris products. Selected citations for Decynium 22 include:
1 Citation: Showing 1 - 1
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Downregulation of miR-7116-5p in microglia by MPP+ sensitizes TNF-α production to induce dopaminergic neuron damage.
Authors: He Et al.
Glia 2017;65:1251
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