Dextromethorphan hydrobromide
Chemical Name: (9α,13α,14α)-3-Methoxy-17-methylmorphinan hydrobromide
Purity: ≥99%
Biological Activity
Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Dextromethorphan is protective against sensitized N-MthD.-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain.
Keller et al.
Eur.J.Neurosci., 2008;27:874 -
Dextrorophan and levorp. selectively block N-MthD.-aspartate receptor-mediated neurotoxicity on corticol neurons.
Choi et al.
J.Pharmacol.Exp.Ther., 1987;242:713
Product Datasheets
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Citation for Dextromethorphan hydrobromide
The citations listed below are publications that use Tocris products. Selected citations for Dextromethorphan hydrobromide include:
1 Citation: Showing 1 - 1
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Milled Stress Reduces Morphine-Induced Locomotion in F2 NMRI Mice.
Authors: Ghoshooni Et al.
Pharmacol Res Perspect 2011;10:347
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