- Products
- Our Products
- Services
- Protein Custom Services
- Assay Custom Services
- Antibody Custom Services
- Monoclonal Antibody Panels
- Recombinant Antibody Conversion
- Luminex Custom Services
- Custom Cell Culture Media Services
- Biomarker Testing Services
- Chemistry Services
- Custom Compound Libraries
- Bioactivity Testing Services
- Bulk/Custom Formulation
- Ubiquitin/Proteasome Custom Services
- Custom cDNA Cloning
Expedite Your Research
Expedite Your Research
- Pathways
- Resources
- Research Areas
- Protocols/Troubleshooting Guides/Videos
- Technical Information
- Articles
- Help & FAQs
- Literature
- Request Literature
- Calculators
- Posters
- Blog
- Promotions
- Travel Grants
Posters, Brochures, Whitepapers & Reference Guides
Request Literature
- R&D Systems Quality
- Quality Philosophy
- People
- Place
- Performance
- Product Development
- Customer Satisfaction
- The R&D Systems Quality Advantage
- Documents, Certifications, & FAQs
Experts in Reagent Quality
R&D Systems Quality
- About Us
- Careers
- Bio-Techne Brands
- Investor Relations
Our People are Our Greatest Asset
Join Us
- Contact Us
Catalog Number:4523
Chemical Name:4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).
ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).
Technical Data
-
M.Wt:498.48
-
Formula:C16H8N2Na2O6S4
-
Solubility:Soluble to 10 mM in DMSO and to 10 mM in Potassium bicarbonate (0.1M)
-
Purity:>95
-
Storage:Store at +4°C
-
CAS No:67483-13-0
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:
The citations listed below are publications that use Tocris products. Selected citations for DIDS include:
2
Citations: Showing 1 -
2
Filter your results:
|
||
VersaClone cDNA Plasmids
Description
Application
Cat#
Citations
Images
Rat Vanilloid R1/TRPV1 (NP_114188) VersaClone cDNA
RDC1967
View Sizes & Prices
| Catalog# | Size | Price | Stock | Quantity |
|---|---|---|---|---|
Loading Information....
Average Rating: 5
(Based on 1 review)
Have you used DIDS?
Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.
Read what people are saying who have used DIDS.
We have 1 review tested in 1 species: Rat.
Filter by Ratings
Excellent
(1)
All Ratings
Filter by Applications
All Applications
Filter by Species
Rat
(1)
All Species
| Images | Ratings | Applications | Species | Reviewed By | Date | Details | ||
|---|---|---|---|---|---|---|---|---|
|
Excellent |
Rat | Anonymous | 02/06/2018 |
Summary
|
Please scroll the above reviews for more
Tocris Bioscience is the leading supplier of novel and exclusive tools for
life science research with over 30 years' experience in the industry.
Tocris is a Bio-Techne brand.