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DLPC

Catalog #: 4378
2 Citations Datasheet / COA / SDS

Discontinued Product

4378 has been discontinued.
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DLPC | CAS No. 18194-25-7 | Nuclear Receptor Agonists
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Description: LRH-1 agonist; regulates bile acid metabolism

Chemical Name: (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.

Technical Data

M.Wt:
621.83
Formula:
C32H64NO8P
Solubility:
Soluble to 100 mM in ethanol
Storage:
Store at -20°C
CAS No:
18194-25-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for DLPC

The citations listed below are publications that use Tocris products. Selected citations for DLPC include:

2 Citations: Showing 1 - 2

  1. Tankyrase inhibition promotes a stable human na�ve pluripotent state with improved functionality.
    Authors: Zimmerlin Et al.
    Development  2016;143:4368
  2. Mouse liver repopulation with hepatocytes generated from human fibroblasts.
    Authors: Zhu Et al.
    Nature  2014;508:93

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