Catalog Number: 4378
Chemical Name: (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
Biological Activity
Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.
Technical Data
  • M.Wt:
    621.83
  • Formula:
    C32H64NO8P
  • Solubility:
    Soluble to 100 mM in ethanol
  • Storage:
    Store at -20°C
  • CAS No:
    18194-25-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.
    Lee et al.
    Nature, 2011;474:506
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DLPC include:

1 Citations: Showing 1 - 1

  1. Mouse liver repopulation with hepatocytes generated from human fibroblasts.
    Authors: Zhu Et al.
    Nature 2014;508:93

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