DMPO
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Description: Nitric oxide spin trap; measure oxygen-centered free radicals
Chemical Name: 3,4-Dihydro-2,2-dimethyl-2H-pyrrole 1-oxide
Biological Activity
Water soluble nitric oxide spin trap; allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance (ESR). Has a high reaction rate constant for superoxide and hydroxyl radicals, and distinguishes simultaneously among a variety of important biologically generated free radicals.Technical Data
M.Wt:
113.16
Formula:
C6H11NO
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store at -20°C
CAS No:
3317-61-1
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Analysis of hepatic oxidative stress status by electron spin resonance spectroscopy and imaging.
Togashi et al.
Free Radic.Biol.Med., 2000;28:846 -
The generation of lucigenin chemiluminescence from the reaction of guanidino compounds with phenylglyoxal under alkaline conditions and its application.
Nohara et al.
Chem.Pharm.Bull., 2009;57:700 -
Comparison of superoxide detection abilities of newly developed spin traps in the living cells.
Saito et al.
Free Radic.Res., 2009;43:668
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