Biological Activity Endogenous σ1 receptor ligand and psychoactive plant compound (Ki = 14.8 μM). Binding to σ1 inhibits voltage-gated Na+ channels and is responsible for the behavioral effects of DMT. Also a 5-HT2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (Ki = 4.0 μM).
Soluble to 5 mM in ethanol
Store at -20°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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