Catalog Number: 2863
Alternate Names: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride
Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzeneethanamine hydrochloride
Biological Activity
Selective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Selectivity of serotonergic drugs for multiple brain serotonin receptors.
    Titiler et al.
    Biochem.Pharmacol., 1987;36:3265
  2. A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex.
    Arvanov et al.
    Eur.J.Neurosci., 1999;11:2917
  3. Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin.
    McKenna et al.
    J.Neurosci., 1989;10:3482
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