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DOB hydrochloride

Catalog #: 2863 Datasheet / COA / SDS

Discontinued Product

2863 has been discontinued.
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DOB hydrochloride | CAS No. 29705-96-2 | Non-selective 5-HT2 Receptor Agonists
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Description: Selective 5-HT2 agonist
Alternative Names: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride

Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzeneethanamine hydrochloride

Purity: ≥99%

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Biological Activity

Selective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.

Technical Data

M.Wt:
310.62
Formula:
C11H16BrNO2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Store at RT
CAS No:
29705-96-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Selectivity of serotonergic drugs for multiple brain serotonin receptors.
    Titiler et al.
    Biochem.Pharmacol., 1987;36:3265
  2. A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex.
    Arvanov et al.
    Eur.J.Neurosci., 1999;11:2917
  3. Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin.
    McKenna et al.
    J.Neurosci., 1989;10:3482

Product Datasheets

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