DOK4 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-33274

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DOK4 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSEL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DOK4 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: DOK4 Antibody [NBP2-33274]

Immunocytochemistry/ Immunofluorescence: DOK4 Antibody [NBP2-33274]

Immunocytochemistry/Immunofluorescence: DOK4 Antibody [NBP2-33274] - Immunofluorescent staining of human cell line CACO-2 shows localization to microtubules & cytokinetic bridge.
Immunohistochemistry-Paraffin: DOK4 Antibody [NBP2-33274]

Immunohistochemistry-Paraffin: DOK4 Antibody [NBP2-33274]

Immunohistochemistry-Paraffin: DOK4 Antibody [NBP2-33274] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for DOK4 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DOK4

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells

Long Name

Docking Protein 4

Alternate Names

docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, Insulin receptor substrate 5, IRS5, IRS-5

Gene Symbol

DOK4

UniProt

Q8TEW6

Additional DOK4 Products

Product Documents for DOK4 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DOK4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

GDNF Family

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Protocols

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FAQs

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