Dopa Decarboxylase/DDC Antibody (CL2962)

Novus Biologicals | Catalog # NBP3-52076

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # CL2962
View all Dopa Decarboxylase/DDC Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P20711, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Dopa Decarboxylase/DDC Antibody (CL2962)

Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of mouse substantia nigra shows strong positivity in dopamine neurons in pars compacta.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of human fallopian tube shows no positivity in glandular cells as expected.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Analysis in human kidney and fallopian tube tissues. Corresponding Dopa Decarboxylase/DDC RNA-seq data are presented for the same tissues.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of rat substantia nigra shows strong positivity in dopamine neurons in pars compacta.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Dopa Decarboxylase/DDC Antibody (CL2962) Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Immunohistochemistry: Dopa Decarboxylase/DDC Antibody (CL2962) [NBP3-52076]

Staining of human substantia nigra shows cytoplasmic positivity in dopamine neurons in pars compacta.

Applications for Dopa Decarboxylase/DDC Antibody (CL2962)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopa Decarboxylase/DDC

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Alternate Names

AADC, DDC

Gene Symbol

DDC

Additional Dopa Decarboxylase/DDC Products

Product Documents for Dopa Decarboxylase/DDC Antibody (CL2962)

Certificate of Analysis

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Product Specific Notices for Dopa Decarboxylase/DDC Antibody (CL2962)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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