Drebrin 1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-38650

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Drebrin 1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Drebrin 1 Antibody - BSA Free

Drebrin 1 Antibody

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] -

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] -Analysis in human cerebral cortex and liver tissues using NBP2-38650 antibody. Corresponding DBN1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] - Staining of human cerebral cortex, kidney, pancreas and testis using Anti-DBN1 antibody NBP2-38650 (A) shows similar protein distribution across tissues to independent antibody NBP2-38813 (B).
Immunocytochemistry/ Immunofluorescence: Drebrin 1 Antibody [NBP2-38650]

Immunocytochemistry/ Immunofluorescence: Drebrin 1 Antibody [NBP2-38650]

Immunocytochemistry/Immunofluorescence: Drebrin 1 Antibody [NBP2-38650] - Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & actin filaments.
Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] - Staining of human cerebral cortex shows high expression.
Drebrin 1 Antibody

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] -

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] - Staining of human testis shows strong membranous positivity in spermatogonia.
Drebrin 1 Antibody

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] -

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-38650] - Staining of human kidney shows strong membranous positivity in cells in tubules.

Applications for Drebrin 1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Drebrin 1

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

UniProt

Q16643 (Human)

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Drebrin 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Neuronal Markers

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Protocols

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