Adrenergic neurotoxin. Displays neurotoxic effects on both peripheral and central noradrenergic neurons.
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DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats.
Jaim-Etcheverry and Zieher
Brain Res., 1980;188:513
Short and long term analysis of heart rate variations in spontaneous hypertensive rats: effect of DSP-4 administration.
Kawamura et al.
Denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 [N(2-chloroethyl)-N-ethyl-2-bromobenzylamine] reduces dopamine release potential in the nucleus accumbens shell in conscious rats.
Haidkind et al.
The citations listed below are publications that use Tocris products. Selected citations for DSP-4 include:
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