DYRK1A Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76559

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DYRK1A Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human DYRK1A. The immunogen is located within the last 50 amino acids of DYRK1A. Amino Acid Squence: LTMRQGADREESPMTGV

Specificity

Multiple isoforms of DYRK1A are known to exist. DYRK1A antibody will not cross-react with other DYRK family members

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DYRK1A Antibody - BSA Free

Western Blot: DYRK1A AntibodyBSA Free [NBP1-76559]

Western Blot: DYRK1A AntibodyBSA Free [NBP1-76559]

Western Blot: DYRK1A Antibody [NBP1-76559] - Western blot analysis of DYRK1A expression in K562 cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/ml.
Western Blot: DYRK1A AntibodyBSA Free [NBP1-76559]

Western Blot: DYRK1A AntibodyBSA Free [NBP1-76559]

Western Blot: DYRK1A Antibody [NBP1-76559] - Analysis of DYRK1A in HeLa cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/mL.
DYRK1A Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: DYRK1A Antibody - BSA Free [NBP1-76559] -

Immunocytochemistry/ Immunofluorescence: DYRK1A Antibody - BSA Free [NBP1-76559] - Immunocytochemistry of DYRK1A in HeLa cells with DYRK1A antibody at 10 ug/mL.

Applications for DYRK1A Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10 ug/mL

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DYRK1A

DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family and is thought to be involved in neuronal differentiation, neurodegenerative diseases, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. DYRK1A phosphorylates several transcription factors such as p53, leading to inhibition of embryonic neuronal cell proliferation. DYRK1A associates with multiple proteins, including SPRED1 and SPRED2; this association appears to inhibit the phosphorylation activity of DYRK1A. Recent evidence also suggests that DYRK1A may be involved in the replication of HIV-1.

Long Name

Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinase 1A

Alternate Names

MNBH

Gene Symbol

DYRK1A

UniProt

NP_001387 (Human)

Additional DYRK1A Products

Product Documents for DYRK1A Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DYRK1A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Intracellular Kinases
Notch Pathway

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail