Catalog Number: 3058
Chemical Name: 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
Biological Activity
Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk� and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.
Technical Data
  • M.Wt:
    302.19
  • Formula:
    C14H6O8
  • Solubility:
    Soluble to 0.65 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    476-66-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.
    Cozza et al.
    J.Med.Chem., 2006;49:2363
  2. Antioxidant and apoptosis-inducing activities of ellagic acid.
    Han et al.
    Anticancer Res., 2006;26:3601
  3. The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin.
    Hayeshi et al.
    Food Chem.Toxicol., 2007;45:286

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