EMDT oxalate
Chemical Name: 2-Ethyl-5-methoxy-N,N-dimethyl-1H-indole-3-ethanamine oxalate
Purity: ≥98%
Biological Activity
Selective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors). Exhibits potency comparable to serotonin for the activation of adenylate cyclase. Displays antidepressant-like effects.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors.
Glennon et al.
J.Med.Chem., 2000;43:1011 -
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation.
Svenningsson et al.
J.Neurosci., 2007;27:4201
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