Chemical Name:10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate
Biological Activity Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat and human mast cells. Results in the abrogation of degranulation, TNF-α production (IC50 = 10 μM) and other related signaling events.
Soluble to 75 mM in water and to 100 mM in DMSO
Desiccate at +4°C
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you
include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image.
Limited to verified customers in USA, Canada and Europe.
Read what people are saying who have used ER 27319 maleate.
We have 1 review tested in 1 species: Human.
Filter by Ratings
Filter by Applications
Filter by Species
Please scroll the above reviews for more
Tocris Bioscience is the leading supplier of novel and exclusive tools for
life science research with over 30 years' experience in the industry.
Tocris is a Bio-Techne brand.