Phosphodiesterase inhibitor, selective for PDE4 (IC50
= 2.0 μ
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All Tocris products are intended for laboratory research use only.
Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes.
Nicholson et al.
1-Ethyl-4-(isopropylidenehydrazinol-H-pyrazolo-(3,4-b)-pyridin-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009) - potent new inhibitor of cyclic 3'5-nucleotide phosphodiesterase.
Chesin et al.
Selective inhibition of cyclic AMP and cyclic GMP phosphodiesterases of cardiac nuclear fraction.