Exosome component 10 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-82447

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Exosome component 10 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Exosome component 10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Exosome component 10 Antibody [NBP1-82447]

Immunocytochemistry/ Immunofluorescence: Exosome component 10 Antibody [NBP1-82447]

Immunocytochemistry/Immunofluorescence: Exosome component 10 Antibody [NBP1-82447] - Staining of human cell line U-2 OS shows localization to nucleus, nucleoli and cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Exosome component 10 Antibody [NBP1-82447]

Immunohistochemistry-Paraffin: Exosome component 10 Antibody [NBP1-82447]

Immunohistochemistry-Paraffin: Exosome component 10 Antibody [NBP1-82447] - Staining of human pancreas shows moderate nucleolar positivity which was combined with distinct cytoplasmic staining in intercalated ducts.

Applications for Exosome component 10 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Exosome component 10

Part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Could be an exonuclease. Plays a role in replication-dependent histone mRNA degradation. Mediates the association of MTR4, C1D and MPP6 wth the exosome and this complex is required for the maturation of 5.8S rRNA. Required for nucleolar localization of C1D

Alternate Names

autoantigen PM-SCL, EC 3.1.13.-, exosome component 10, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, p2, p3, p4, PM/Scl-100Autoantigen PM/Scl 2, PM-Scl, PMSCL2PMSCL, Polymyositis/scleroderma autoantigen 2, polymyositis/scleroderma autoantigen 2 (100kD), polymyositis/scleroderma autoantigen 2, 100kDa, RRP6, Rrp6p, RRP6Polymyositis/scleroderma autoantigen 100 kDa

Gene Symbol

EXOSC10

Additional Exosome component 10 Products

Product Documents for Exosome component 10 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Exosome component 10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Exosome component 10 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Exosome component 10 Antibody - BSA Free and earn rewards!

Have you used Exosome component 10 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Exosome component 10 Antibody - BSA Free

Showing  1 - 1 of 1 FAQ Showing All

  • Q: I'm wondering whether this EXOSC10 Antibody (NBP1-82447) also works for yeast RRP6. Have you guys ever tested that? The reason I'm asking is that the immunogen used (FAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDF) to raise this Ab contains conserved regions between EXOSC10 and yRRP6.

    A:

    We have not tested this antibody for yeast RRP6. However if you would like to test this we can offer you our We have not tested NB600-582 with any dog samples, and cannot guarantee that it will cross-react. However, if you are interested in trying this antibody with dog samples you would be eligible for our Innovators Reward Program. We offer this reward for testing an anitbody with an application or species that we have not yet tested.

Showing  1 - 1 of 1 FAQ Showing All
View all FAQs for Antibodies