Catalog Number: 4113
Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
Biological Activity
PPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.
Technical Data
  • M.Wt:
    360.83
  • Formula:
    C20H21ClO4
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    49562-28-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pleiotropic actions of fenofibrate on the heart.
    Balakumar et al.
    Pharmacol.Res., 2011;63:8
  2. The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.
    Mandard et al.
    J.Biol.Chem., 2004;279:34411
  3. PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice.
    Park et al.
    Kidney Int., 2006;69:1511

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