FGF-BP Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-83904

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all FGF-BP Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DHEFSCVFAGNPTSCLKLKDERVYWKQVARNLRSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETTPSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FGF-BP Antibody - BSA Free

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904] - Analysis in human esophagus and liver tissues. Corresponding FGF-BP RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904] - Staining of human tonsil shows moderate to strong membranous positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904] - Staining of human esophagus shows high expression.
Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904] - Staining of human cervix shows moderate membranous positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody [NBP1-83904] - Staining of human liver shows no positivity in hepatocytes as expected.
FGF-BP Antibody - BSA Free Immunohistochemistry-Paraffin: FGF-BP Antibody - BSA Free [NBP1-83904]

Immunohistochemistry-Paraffin: FGF-BP Antibody - BSA Free [NBP1-83904]

Staining of human skin shows strong membranous positivity in squamous epithelial cells.
FGF-BP Antibody - BSA Free Western Blot: FGF-BP Antibody - BSA Free [NBP1-83904]

Western Blot: FGF-BP Antibody - BSA Free [NBP1-83904]

Analysis in human cell lines A-431 and MCF-7 using Anti-FGFBP1 antibody. Corresponding FGFBP1 RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.

Applications for FGF-BP Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGF-BP

FGFBP1, also known as Fibroblast growth factor-binding protein 1, is a 234 amino acid protein that is approximately 26 kDa, acts as a carrier protein that release fibroblast-binding factors (FGFs) enhancing its mitogenic activity and can be found secreted, in extracellular space and cell membrane. This protein is currently being studied for research on the following diseases and disorders: squamous cell carcinoma, breast cancer, colon cancer, pancreatitis, hypertension, narcolepsy, ataxia, prostatitis, and peritonitis. FGFBP1 has also been shown to have interactions with FGF2, FIBP, NRP2, UBQLN4 and HSPG2 in pathways such as the positive regulation of fibroblast growth factor receptor signaling pathway, positive and negative regulation of cell proliferation, cell-cell signaling and signal transduction.

Long Name

Fibroblast Growth Factor Binding Protein

Alternate Names

FGF-BP1, FGFBP, FGFBP-1, FGFBP1, HBp17

Gene Symbol

FGFBP1

Additional FGF-BP Products

Product Documents for FGF-BP Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for FGF-BP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Developmental Biology
FGF Family

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Protocols

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