FKBP51/FKBP5 Antibody (OTI3E9)

Novus Biologicals | Catalog # NBP1-47755

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3E9
View all FKBP51 Primary Antibodies »

Product Specifications

Immunogen

Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Specificity

This antibody is specific for Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

51.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FKBP51/FKBP5 Antibody (OTI3E9)

Western Blot: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Western Blot: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Western Blot: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FKBP5/FKBP51 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FKBP5/FKBP51.
Immunocytochemistry/Immunofluorescence: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FKBP5/FKBP51.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded prostate tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded Carcinoma of thyroid tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded colon tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded endometrium tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP51/FKBP5 Antibody (OTI3E9) [NBP1-47755]

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded pancreas tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.

Applications for FKBP51/FKBP5 Antibody (OTI3E9)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FKBP51

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Long Name

51 kDa FK506 Binding Protein

Alternate Names

Dit1, FKBP5, FKBP54, Ptg-10

Entrez Gene IDs

2289 (Human)

Gene Symbol

FKBP5

Additional FKBP51 Products

Product Documents for FKBP51/FKBP5 Antibody (OTI3E9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for FKBP51/FKBP5 Antibody (OTI3E9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Phosphatases and Regulators

Customer Reviews for FKBP51/FKBP5 Antibody (OTI3E9)

There are currently no reviews for this product. Be the first to review FKBP51/FKBP5 Antibody (OTI3E9) and earn rewards!

Have you used FKBP51/FKBP5 Antibody (OTI3E9)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies