Flunarizine dihydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. The ability of diphenylpiperazines to prevent neuronal death in dorsal root ganglion neurons in vitro after axotomy.
   Eichler et al.
   J.Neurochem., 1994;62:2148
3. Pharmacological modulation of voltage gated Na⁺ channels: a rational and effective strategy against ischemic brain damage.
   Urenjak and Obrenovitch
   Pharmacol.Rev., 1996;48:21
4. Ca⁺ and Na⁺ channels involved in neuronal cell death - protection by flunar.
   Pauwels et al.
   Life.Sci., 1991;48:1881

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