Potent inhibitor of cyclooxygenase (IC50
values are 0.1 and 0.4 μ
M for inhibition of human COX-1 and COX-2 respectively). Analgesic, anti-inflammatory and antipyretic in vivo
. Inhibits tumor cell growth in vitro
and in vivo
. Regulates prostate stem cell antigen through activation of Akt kinase. Also inhibits fibroblast proliferation in vitro
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All Tocris products are intended for laboratory research use only.
The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A potent non-steroidal anti-inflammatory drug.
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The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
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Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.
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Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase.
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