FoxP2 Antibody

Novus Biologicals | Catalog # NB100-55411

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Feline (100%), Porcine (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Peptide ELISA, Immunocytochemistry/ Immunofluorescence, Chromatin Immunoprecipitation (ChIP)

Cited:

Immunohistochemistry-Frozen, Immunocytochemistry/ Immunofluorescence, Chemotaxis

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all FoxP2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-DEVEYQKRRSQKIT corresponding to internal region according to NP_055306.1, NP_683696.2, NP_683697.2, NP_683698.2, NP_001166237.1.

Epitope

DEVEYQKRRSQKIT

Reactivity Notes

Mouse reactivity reported in the scientific literature (PMID: 23821603). Use in Rat reported in scientific literature (PMID:18239190).

Specificity

This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.2), isoform IV (NP_683698.2) and isoform V (NP_001166237.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FoxP2 Antibody

Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411]

Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411]

Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411] - Staining of paraffin embedded Human Placenta. Antibody at 2.5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411]

Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411]

Immunohistochemistry-Paraffin: FoxP2 Antibody [NB100-55411] - Human prostate. Antibody at 2.5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for FoxP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500

Immunohistochemistry

2.5 ug/mL

Immunohistochemistry-Frozen

2.5 ug/mL

Immunohistochemistry-Paraffin

2.5 ug/mL

Peptide ELISA

Detection limit 1:64000
Application Notes
Use in Chromatin Immunoprecipitation reported in scientific literature (PMID:18239190).ICC/IF, IHC-Fr reported in (PMID: 23821603).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FoxP2

This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

Long Name

Forkhead Box P2

Alternate Names

CAGH44, SPCH1, TNRC10

Entrez Gene IDs

93986 (Human); 114142 (Mouse); 500037 (Rat)

Gene Symbol

FOXP2

UniProt

NP_055306.1 (Human)

Additional FoxP2 Products

Product Documents for FoxP2 Antibody

Certificate of Analysis

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Product Specific Notices for FoxP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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