Chemical Name:2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid
Biological Activity Selective PKCε activator that displays > 7-fold selectivity over other PKC isozymes. Stimulates glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. Brain penetrant.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at -20°C
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